REACTIVE OXYGEN SPECIES-RESPONSIVE NANOCOCKTAIL WITH SELF-AMPLIFICATED DRUG RELEASE FOR EFFICIENT CO-DELIVERY OF PACLITAXEL/CUCURBITACIN B AND SYNERGISTIC TREATMENT OF GASTRIC CANCER

Application of drug combinations is a powerful strategy for the therapy of advanced gastric cancer.However, the clinical use Apple Corer of such combinations is greatly limited by the occurrence of severe systemic toxicity.Although polymeric-prodrug-based nanococktails can significantly reduce toxicity of drugs, they have been shown to have low int

Abstract This paper presents a review of current techniques employed for dynamic analysis of concrete gravity dams under seismic Breads action.Traditional procedures applied in design bureaus, such as the Pseudo-Static method, often neglect structural dynamic properties, as well as ground amplification effects.A practical alternative arises with th